metformin or semaglutide for weight loss vs. Metformin Vs. Semaglutide: Drug Comparison

adults have obesity or are overweight, conditions "associated with some leading causes of death, including heart disease, stroke and diabetes, and is linked to an increased risk of certain types of cancer," the FDA says

This warning stems from preclinical studies in rodents that demonstrated dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures

doi: 10.1021/ac200998a

This consensus-based guidance, which includes an outline of eight key nutritional priorities to support patients on GLP-1 medications, reflects the top interdisciplinary recommendations to help clinicians support patients receiving GLP-1 receptor agonists for obesity care with evidence-based nutritional and behavioral strategies

Several factors may explain this: Weight loss and body confidence : Losing weight, particularly when it has been a long-standing source of distress, can significantly improve self-esteem and reduce symptoms of depression and anxiety