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TRT has direct metabolic effects, including: Muscle growth : Testosterone directly stimulates muscle protein synthesis, growth, and repair, especially of the fast-twitch muscle fibers that power strength and hypertrophy, says Lee

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Cunnane et al., 2020

Similar to the protease discussed in the context of stroke, MS, and ALS, the cell-signaling analog of activate protein C, 3K3A-activated protein C, in addition to improving cerebrovascular integrity also diminished neuroinflammatory responses and slows the generation of amyloid-beta plaque buildup in AD model mice [129]