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While STEP-HFpEF was underpowered to truly detect outcome differences, the difference observed supports the need for larger, outcomes-driven trials in obese patients with HFpEF

FOXO4-DRI was apparently linked to lower levels of senescence markers (p53, p21, p16) and lower levels of several Senescence-Associated Secretory Phenotype factors in such cell cultures, especially IL-1, IL-6, and TGF-

[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Meuwese CL, Dekker FW, Lindholm B, et al

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1 Introduction: background and premise The association between neurodevelopmental disorders (NDDs) and certain types of cancers has been implicated in several epidemiological studies