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Persistent mitochondrial ROS generation leads to lipid peroxidation, increased membrane permeability, mitochondrial uncoupling, and inflammatory signalling via tumor necrosis factor-alpha (TNF-), thereby perpetuating hepatocellular damage [55, 56]

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September 18, 2024 GlaxoSmithKline reaches settlements in California state court over cancer allegations, with the deal amounts undisclosed

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