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GLP-1 receptor agonists (such as semaglutide) mimic the GLP-1 gut hormone and act on GLP-1 receptors throughout the body, including the brain

References 1.Jzwiak M., Bauer M., Kamysz W., Kleczkowska P

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Notably, this gastric emptying effect tends to attenuate over time with continued treatment, while the medication's effects on weight and blood glucose control persist

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