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The drawbacks of using BCH as an LAT1 inhibitor are its low selectivity and low affinity, which require high concentrations to exert inhibitory effects [68]

To translate this potent therapeutic promise into a clinical reality, future research must successfully navigate four interconnected pivotal challenges

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doi: 10.1016/j.cmet.2019.12.007 19 DaiEZhangWCongDKangRWangJTangDet al

10.1046/j.1460-9568.2000.00229.x Eur J Neurosci