10a, knocking down CBS in HepG2 cells primarily elevated the expression of a number of mesenchymal markers (e.g., COL3A1 ) that were also induced in HNF4-depleted HepG2 cells, whereas knocking down other SAA enzymes modestly reduced the expression of two epithelial markers that were repressed in HNF4 depleted cells
The way to accomplish this is by improving function at the cellular level
Diabetes 12 , 14631478 (2021)
Ma Y, Shi Y, Wu Q et al (2021) Dietary arsenic supplementation induces oxidative stress by suppressing nuclear factor erythroid 2-related factor 2 in the livers and kidneys of laying hens
To evaluate growth on solid media, in all cases -with the exception of the metE mutant, which only grew in the presence of B12 and, therefore, plating with and without B12 was performed from liquid cultures supplemented with B12- the liquid cultures grown without B12 were plated in solid 7H10-ADC plates supplemented with or without AdoCbl (10 g/mL) and/or L-Met (25 g/mL)