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Patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should not use tirzepatide, as GLP-1 receptor agonists have been associated with thyroid C-cell tumors in rodent studies

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Dose Escalation Without Price Changes at PlexusDx A unique PlexusDx benefit is the pricing model: your dose may need to increase over weeks or months as your body adapts, but your monthly cost remains flat