Common side effects of sitagliptin include: Diarrhea Headache Nausea Sore throat Stuffy or runny nose Swelling of hands or legs Upper respiratory infection Serious sitagliptin side effects include: Allergic reactions (hives, difficulty breathing or swelling of the lips, face, tongue or throat) Heart failure (rapid increase in weight, shortness of breath or swelling of the feet) Hypoglycemia (low blood sugar) Necrotizing pancreatitis (a complication of acute pancreatitis that causes tissue death) Acute pancreatitis (inflammation in the pancreas, causing abdominal pain) Severe joint pain Severe skin reaction (rash, blistering or peeling, burning eyes or facial swelling) Increased blood glucose, pancreatitis, pancreatic cancer and gastrointestinal disorders (vomiting, diarrhea and nausea) were the most commonly reported side effects of Januvia and Janumet to the FDAs Adverse Event Reporting System (FAERS)
Targeted disruption of the glutaredoxin 1 gene does not sensitize adult mice to tissue injury induced by ischemia/reperfusion and hyperoxia
they represent a reproducible pattern across multiple substances and multiple study designs
Understanding your genetic predispositions in these appetite-regulating genes can support a more informed conversation with your healthcare provider about whether GLP-1 treatment aligns with your individual biology and binge eating profile
Venous outflow is unobstructed by decompressing these nerves
