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People with untreated hypothyroidism should delay sermorelin until their thyroid condition is managed, because low thyroid hormone levels can make sermorelin ineffective (thyroid hormone is important for growth hormone action)

The normal thyroid scan (left) allows identification of a thyroid with normal stable (127I) stores throughout both lobes

Users may experience water retention, heightened hunger, and alterations in insulin response

Who may qualify for Retatrutide if approved

Limitations include that the data came from 1 health system in the US, most patients were white, and it was unknown why patients were prescribed this medication, although 93% were diabetic