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In the present study, STZ-induced diabetic rats exhibited marked increases in proinflammatory cytokines including TNF-, IL-6, and NFkB-1 within hippocampal tissue, highlighting a pronounced neuroinflammatory state

Adults with a BMI of 30 or above , or adults with a BMI of 27 or above who also have at least one weight-related health condition such as high blood pressure, type 2 diabetes, or high cholesterol

Nontraditional markers of glycemia: associations with microvascular conditions

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It is unknown whether OZEMPIC causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of semaglutide-induced rodent thyroid C-cell tumors has not been determined [see Warnings and Precautions (5.1) and Nonclinical Toxicology (13.1)]