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If the benefit holds, the intervention changed something durable about the tissue, its connectivity, its vasculature, or its cellular state, which makes it neurorestorative

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[1] While some fatty acids can, long chain fatty acids cannot pass through the mitochondrial membrane

Underlying conditions such as hypothyroidism, Cushing's syndrome, PCOS, or obstructive sleep apnoea can blunt weight loss responses and should be investigated if not already excluded

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