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SubQ Dosing Schedule (Research/Community) Week / Phase Weeks 1-2 Dose per Injection (mcg) 100 mcg Frequency 3x daily, at least 4 hours apart Week / Phase Weeks 3-4 Dose per Injection (mcg) 200 mcg Frequency 3x daily, at least 4 hours apart Week / Phase Weeks 5-12 Dose per Injection (mcg) 300 mcg Frequency 3x daily, at least 4 hours apart Educational only

Kidney International , 105 (4S), S117314