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This system rated cartilage structural integrity from 0, defined as normal to 6, defined as complete disorganization, and assessed cellularity from 0, defined as normal, to 3, defined as hypocellularity, for a total possible score of 0 to 9

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By inhibiting NNMT activity, 5-Amino-1MQ modulates enzymatic processes associated with nicotinamide metabolism, methylation network regulation, and intracellular cofactor-associated signaling systems