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For in vitro cytotoxicity assays where benzyl alcohol vehicle effects could confound results, include matched Bacteriostatic Water vehicle controls at the same final benzyl alcohol concentration as the peptide treatment to distinguish compound-specific from vehicle-associated biological effects

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Nitric oxide relaxes the smooth muscles and causes vasodilation and an increase in the blood flow

Therefore, clinicians should focus on long-term trends rather than short-term fluctuations