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Oxidative stress is one of the many causes of diseases like diabetes, arthritis and cancer

What animal models and community sources describe: Anti-catabolic signaling activates within hours

C: JNK protein levels in control and in HPV-16 E7- and in HPV-16 E7 Mut-expressing HaCaT cells that were untreated or cells that were sampled after induction of oxidative stress by exposure to UV (UVB, 5 mJ/cm2 for 1 min) with a 5 h recovery period, evaluated using an antibody specific for the phosphorylated form of JNK (pJNK) and another antibody that detects total JNK levels (JNK, performed on a separate twin gel)

It was particularly satisfying to find that secondary carbonates can substantially improve prodrug stability while maintaining efficient glutathione-triggered release - a design principle that may prove useful for future bio-responsive prodrugs

doi: 10.1007/s13402-016-0274-8 166 LiDDianYLiLDuSMengYYaoLet al