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Semaglutide can reduce thirst cues alongside appetite, so many users need to set reminders or use marked water bottles to ensure adequate intake

Phentermine is usually taken for a few weeks until tolerance develops

Its safe for long-term use under medical supervision

Bonnet, who co-authored a major clinical advisory on nutrition and GLP-1 therapy, said the key to success with GLP-1s is pairing the drugs with lifestyle changes healthier food choices and more activity

Nevertheless, it is crucial to consider the potential adverse effects of weight fluctuation after discontinuing these medications, particularly the increased risk of cardiovascular and all-cause mortality in patients with obesity or overweight