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A 2021 medical review on the safety of semaglutide documented the following side effect rates: nausea occurred in upwards of 20% of patients, vomiting occurred in 4% to 11.5% of patients, and diarrhea occurred in 4.5% to 11.3% of patients

Individual timelines vary based on starting blood pressure, weight loss rate, and concurrent medications

Treatment and prevention involve eating meat, fish, and dairy products or foods fortified with B12, like some breakfast cereals and breads