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Nat Rev Rheumatol 19 , 96110 (2023)

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After reviewing these relevant studies, 13 studies demonstrated that lycopene could significantly refine the clinical manifestations of OSF patients, among which 12 randomized controlled trial (RCT) studies have compared the potential efficacy between lycopene and other treatment modalities or the combinational effectiveness of lycopene with other drugs, apart from one study by Arakeri et al

Several studies have previously reported the inhibitory effect of selenium on kidney stones

Joint or muscle tightness: Rapid tissue hydration and growth can cause temporary stiffness or mild discomfort