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To this end, high-fat-diet (HFD) feeding in mice has been shown to induce beta-cell-like changes in the electrical profile of a subset of alpha-cells (73)

Semaglutide offers a more sustainable solution by addressing the underlying issues of appetite control and insulin sensitivity

[DOI] [PubMed] [Google Scholar] 60.van Klaveren R.J., Demedts M., Nemery B

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In addition to their glucose-lowering properties with low risk of hypoglycaemia, GLP-1RAs reduce body weight and show promising results in reducing cardiovascular risk and renal complications in high-risk individuals with T2D