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however, it did not seem to increase immune-related adverse effects or affect their safety profile [66]

Notably, the present narrative review is an extension of a previous review article that covered polyphenols and/or phytoestrogens that included daidzein, equol, genistein, and resveratrol as supplemental therapies for skin aging, which was published in Dermatology and Therapy earlier this year by Lephart (2025) [9]

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