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DOI : 10.3390/nu16111629, Hewlings, S

After stopping, it takes roughly 5 half-lives (about 30 days) for the compound to clear

Dysesthesia A notable finding was dysesthesia (an abnormal sensation such as tingling, burning, or numbness), reported in up to 20.9% of participants at the 12 mg dose

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Depletion of GSH with the GCL inhibitor BSO leads to gliosis and neuroinflammation in the rat brain, with a particular increase in levels of TNF ( Oxidative stress involves the damage to mtDNA, lipids, and proteins in the cell which can lead to neuroinflammation