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Key warning signs include: Discolouration : Any yellow, brown, or pink tinting indicates chemical degradation Cloudiness or turbidity : The solution should remain crystal clear

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That small drop of liquid you see on the skin after a rushed injection

Although some patients develop a mild rash to allopurinol that remains mild over time, or respond to antihistamines, continuing the allopurinol despite a rash is not advised, since the rash can worsen unpredictably