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In the STEP-1 clinical trial, participants lost an average of 15.3 kilograms (33.7 pounds), with approximately 6.9 kilograms (15.2 pounds) coming from lean tissue

Van Schaik L, Kettle C, Green R, Irving HR, Rathner JA (2021) Effects of caffeine on brown adipose tissue thermogenesis and metabolic homeostasis: a review

Docusate sodium (Docusol, DulcoEase) is a stool softener that works by increasing water and fat penetration into the stool

A pivotal study published in the Journal of Clinical Endocrinology and Metabolism investigated the effects of GLP-1 receptor agonists, including semaglutide, on urinary excretion patterns