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This initial loss reflects reduced calorie intake rather than increased calorie burning, since appetite suppression makes it effortless to consume fewer calories without deprivation

37 Thus, outcomes relevant for seeking accelerated approval during future phase III RCTs with a longer duration of follow-up are ongoing

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doi: 10.1007/s10620-024-08720-2 103 ClarkeLPassamRTFalaheeBJirapinyoPAllegrettiJRKellyCR