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Description

DSIP is found in both free and protein-bound forms in the hypothalamus, limbic system, and pituitary gland, as well as in peripheral organs including the gut secretory cells, pancreas (where it co-localises with glucagon), and plasma with brain and plasma DSIP concentrations showing a marked diurnal variation that correlates with circadian rhythm in humans, with levels lowest in the morning and higher in the afternoon

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Park JM, Lee HJ, Sikiric P, Hahm KB

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37 Indeed, GLP-1R is present beyond the confines of the pancreas and extends to a multitude of organs and tissues throughout the body

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IL-1stimulated condition studies documented approximately 35% reductions in IL-8 production, with similar patterns observed for IL-6 and IL-1

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1987;252(4 Pt 2):F75760

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