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Glucagon-like peptide-1 receptor agonists, otherwise known as GLP-1s, have surged in popularity for their ability to mimic natural hormones that regulate blood sugar, reduce appetite and slow digestion

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Similarly, a study focusing on CLOCK-related circadian regulators in nurses, found that hypermethylation in BMAL1 gene bodies was associated with working 3 consecutive NS per week, suggesting possible epigenetic silencing affecting CLOCK transcriptional activity