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Yes, reduced food intake from appetite suppression can lead to deficiencies in protein, iron, vitamin D, and B vitamins, all of which are essential for energy production and can contribute to persistent tiredness if not addressed through nutrient-dense eating

This level of weight loss can lead to significant health improvements for many people

Struggling to Lose Weight on Obesity Drugs

The National Center for Complementary and Integrative Health (NCCIH) acknowledges that certain botanical compounds have been studied for glucose management, including berberine, cinnamon extract, and chromium

Don't try to align them they operate on different timescales