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Original Draft Preparation: US and SM

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The impact of age, body mass index, and fish intake on the EPA and DHA content of human erythrocytes

However, the gastrointestinal tract possesses several protective mechanisms, including the acidic pH of gastric fluids, enzymatic degradation activity in the digestive system as well as functional barrier within the intestinal epitheliumall of those factors contribute to a harsh environment for peptide therapeutics and thus, impairment of their stability and absorption behavior [163,304]