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During the first couple of weeks, some patients report: Better skin hydration A healthier-looking glow Calmer, more refreshed-looking skin Early improvement in overall skin texture These early changes are consistent with GHK-Cus studied role in skin support and repair

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CNS GIPR KO mice resist development of diet-induced obesity To generate CNS-specific GIPR KO mice, Gipr fl/fl mice 17 were crossed to synapsin-Cre mice (Jackson Laboratories) to obtain Gipr fl/fl control mice and Gipr Syn/ mice (breeding schematic in Fig