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Numerous other patents and publications describe the use of acetyl L-carnitine and propionyl L-carnitine for therapeutic and/or nutritional purposes, but none of the documents cited above describe these compounds as agents useful for enhancing the efficacy, for example, of sildenafil in the treatment of erectile dysfunction secondary to all those conditions in which there is distress or iatrogenic damage of the lesser pelvis within which the neurovascular bundles of the penis run

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Treatment of Gclc L-KO with GSH-ee reduced the observed increased Nrf2 target gene expression to basal levels in a dose-dependent manner (Fig