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Name: tirzepatide mechanism difference semaglutide Comparative safety and side effects of and tirzepatide: Implications for clinical decision-making in obesity management Retatrutide vs Tirzepatide vs Semaglutide:
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FDA labeling allows staying at the current dose for an extra 4 weeks before stepping up

Phase 3 trials showed weight loss of up to 11.2% at the highest dose over 72 weeks

Used for blood-sugar control in type 2 diabetes

Carnitine also has osmoprotective properties, which can inhibit the activation of transient receptor potential vanilloid type 1 (TRPV1) and protect corneal and conjunctival cells from hyperosmotic stress in dry eye [320]

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