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Although still in its infancy, the novel insights provided by single-cell technologies reveal another way to enhance fibroblasts activity, consisting of activating those subpopulations presenting with pro-repair actions, in contrast or in addition to targeting only the aggressive pathogenic populations (131), may bring novel therapeutic approaches

From Hcy, Cysteine can be produced via the cystathionine betasynthase pathway (CBS), a source of the 1-CC, and can be utilized for the synthesis of glutathione and hypotaurine

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