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And for fitness specifically, the big caveat applies to all of these: rapid weight loss without resistance training and adequate protein costs you a lot of muscle , not just fat

Muscle growth requires a surplus of calories and progressive overload during resistance training

The mechanisms of action for butyrate are due to the fact that it helps regulate gene expression, supports intestinal homeostasis and energy metabolism, and is an anti-inflammatory (Liu et al., 2018)

Pickart and Margolina (2018) review documents broad gene-expression effects in vitro

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