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3k) (also see Supplementary Fig

Increased extracellular and intracellular K + concentrations have been shown to affect glycolysis through Na + /K + -ATPase and pyruvate carboxylase, respectively 104

Four other methylation cycle variables negatively correlated with single estrogen metabolite variables, including betaine, riboflavin (Vit B2), SAM, and the betaine: choline ratio, while total cysteine positively correlated with 2-MeOE1

MRAB are catalase positive and so it is not surprising to see a minimal effect of H 2 O 2 on viability of their biofilms

Therefore, there is a pressing need to explore more efficient methods for target discovery, such as AI-driven technologies, to comprehensively analyze Chinese medicine compound prescriptions and systematically identify novel drug targets