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118 Compared to the hypoinflammatory subphenotype, the hyperinflammatory subphenotype was characterized by higher plasma levels of inflammatory biomarkers, a greater incidence of vasopressor use, lower serum bicarbonate levels, and a greater incidence of sepsis, with higher mortality and fewer ventilator-free days (VFDs) and organ failure-free days in both the ALVEOLI and ARMA cohorts

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MacDougald, Mark C

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Additionally, decreased glycolysis has been observed in CD8+ T cells at rest and after activation (254), CD4+ T cells at rest (254), blood and urine samples (187), and PBMCs (388)