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These conditions can be primary (idiopathic) or secondary to other neurological disorders, such as Parkinson's disease, and are typically managed through physical therapy, medications like anticholinergics, or botulinum toxin injections

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It is also indicated for the prevention and treatment of deficiencies of B complex vitamins, which are essential for the proper functioning of the nervous system and red blood cell production

Validated the recovery rate by measuring both free drug and total drug (after lysis with Triton X-100) to ensure mass balance

Stability of pure metabolites during extraction process in absence of biological sample was monitored by UV-VIS spectroscopy