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When we eat, GLP-1 is released, signaling the pancreas to produce insulin, which helps lower blood sugar levels

A clinical trial using lixisenatide in early Parkinsons patients demonstrated slowed progression of motor symptoms: the treated group had stable MDS-UPDRS Part III scores ( = 0.04), while the placebo group showed worsening disability ( = +3.04) ( Evidence also suggests antidepressant effects of GLP-1RAs

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The number of independent biological samples per group is indicated in the figure legends and the Source Data files

But their impact can extend beyond the scale