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Advise patients with diabetes mellitus on glycemic lowering therapy that they may have an increased risk of hypoglycemia when using WEGOVY and to report signs and/or symptoms of hypoglycemia to their healthcare provider [see Warnings and Precautions (5.4)]

Accordingly, in 2021 we acquired plasma from one hundred children affected with all three stages of konzo along with their discordant sex-matched siblings and utilized the most up-to-date mass spectrometry analysis to assess potential protein differences

In ovariectomized mice (an animal model for menopause), estrogen replacement increased GLP-1 secretion from both intestinal L-cells and pancreatic alpha-cells

Protocol Changes: Based on the nature and severity of side effects, several protocol changes may be appropriate