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SURPASS-CVOT (N=13,165) noninferior on 3-point MACE (HR 0.92), significant on 4-point MACE (0.88) and all-cause death (0.84): Heerspink SURPASS-4 kidney post-hoc

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Increased Hunger: Due to its ghrelin-mimicking action, Ipamorelin can lead to an increased appetite

However, this fear is based on a misunderstanding of how these medications function