In an environment characterized by oxidative stress and mitochondrial dysfunction, the presence of oxLDL further increases the secretion of proinflammatory cytokines (e.g., tumor necrosis factor , interleukin [IL]-6 and IL-1) and the expression of adhesion molecules (including vascular cell adhesion protein [VCAM]-1, monocyte chemoattractant protein [MCP]-1, intercellular adhesion molecule [ICAM]-1 and E-selectin) by monocytes and macrophages ( GLP-1 receptor stimulation appears to attenuate these processes in preclinical models and human studies in various ways
(2017) 171: 628641.e26
Our community is anxiously awaiting the completion of trials and approvals to catch up with real-world use
Khavinson, V., Diomede, F., Mironova, E., Linkova, N., Trofimova, S., Trubiani, O., Caputi, S., & Sinjari, B
These two medications work best when they are incorporated into a well-balanced weight loss plan, including a healthy diet and prioritizing sustainable movement throughout the day
