Serious side effects of the medication include the following: Allergic or hypersensitivity reaction Severe gastrointestinal issues Changes in mood and behavior Pancreatitis Liver problems Low blood sugar levels (hypoglycemia) Cardiac arrhythmias Suicidal ideation Major depressive disorder No adverse event of hypoglycemia or thyroid cancer was reported in Phase II trials, and 7% of retatrutide participants had skin sensitivity, compared to 1% on placebo, but these cases were not serious
Notably, GLP-1 receptor agonists also slow biliary motility, which can contribute to the development of bile ductblocking sludge and stones, resulting in acute pancreatitis
Recently, theyve begun issuing warning letters to some pharmacies, giving them a chance to back off from unfounded claims about their drugs
GLP-1 RAs have also gained momentum to promote weight loss and provide additional health benefits
Her experience, she said, just keeps getting worse. CLARIFICATION: (May 29, 2026, 7:48 p.m