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Contribution of the active metabolite M1 to the pharmacological activity of tesofensine in vivo: a pharmacokinetic-pharmacodynamic modelling approach

A 50% increase in weight loss compared to semaglutide (22.5% vs 14.9%) seems too large to explain as mere enhancement

Managing weight regain Weight regain after bariatric surgery is more common than many people realise

Chronotherapeutic effects of Allu on hyperphagic obesity Impaired diurnal feeding rhythm is implicated in development of obesity, diabetes, and metabolic syndrome in humans and rodents 3,4,28