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Choi, I.-S

While calorie deficits and heavy lifting are foundational, modern science is uncovering that weight management goes far deeper than just "calories in, calories out." It happens at the cellular level

This age-related decline corresponds with observable decreases in skin elasticity, wound healing capacity, and tissue regeneration

For instance, microRNA-375-3p has been shown to alleviate salicylate-induced neuronal injury in vitro by targeting ELAVL4 and subsequently modulating NR2B expression and ROS production, pointing to potential upstream targets for intervention (Zhu et al., 2024)

Immunity 54 , 632647.e639 (2021)