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During a drug holiday specifically, sleep quality becomes even more important because you have lost the medication-driven appetite suppression that previously compensated for suboptimal sleep habits

The worry is that these additives can reduce sterility of the active product and lead to contamination and safety issues

Currently, both agents remain in phase III clinical development pemvidutide for MASLD and survodutide in the SYNCHRONIZE-1 trial specifically evaluating body composition outcomesand have not yet received regulatory approval

Forstner et al., 1998)

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