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In Phase 2 clinical trial (NEJM, 2023), participants on 12 mg dose lost up to 24% body weight over 48 weeks the best result among all weight loss medications

CKD-EPI calculation was used for glomerular filtrate estimation

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Get sufficient sleep during this adjustment period

Essentially they've been tested on animals, but not on humans." He has been watching this market grow for more than a year and has spoken to people who have had side effects such as dizziness, diarrhoea, rashes and leg swelling