Some patients taking GLP-1 drugs to lose weight or manage Type 2 diabetes are discovering an emerging potential side effect from the blockbuster class of medications: the loss of pleasure or an emotional numbness thats been dubbed Ozempic personality. Its not common and doctors dont know if its a direct reaction to the drugs, but it may be a sign to reduce the dose or stop the medication if the impact becomes severe, experts say
In individuals with obesity or overweight and weight-related comorbidities (excluding diabetes), liraglutide at a daily dose of 3.0 mg and semaglutide at a once-weekly dose of 2.4 mgboth GLP-1RAshave demonstrated significant weight reduction
And so-so were-were going from hormesis here to these-these-these areas of, uh, uh, psychology
Tirzepatides efficacy in weight loss is apparent when compared to other diabetes medicines and weight loss drugs
Interestingly, the lysosomotropic compounds chloroquine and tamoxifen have been shown to decrease phagocytosis activity [40] and chloroquine is recognized as a clathrin-dependent endocytosis inhibitor [41]