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Cag acts centrally on amylin receptors in the hypothalamus and brainstem to reduce appetite, lower food intake, suppress post-meal glucagon release, slow gastric emptying, and support improved blood glucose regulation
First, human amylin is aggregation-prone: at pharmaceutical concentrations it readily forms amyloid fibrils, the same class of deposits studied in the context of pancreatic islet pathology
The body responds to this temporary blockade by significantly upregulating its production of endorphinsour natural feel-good molecules that also play a critical role in immune balance
(PubMed) Mazokopakis EE, Starakis IK
Some studies also indicate its potential role in cognitive function and brain health
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