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3.1.1 Nuclear receptor signaling disruption 3.1.1.1 Androgen receptor antagonism Bisphenol A exhibits androgenic antagonism, functioning as a competitive antagonist that blocks androgen receptor binding and subsequently reduces ARE-mediated gene transcription, with documented effects on androgen-dependent gene expression

A systematic review and meta-Analysis revealed that selenium supplementation reduced serum TPOAb levels after 3, 6, and 12 months in an LT4-treated Hashimotos population, and after three months in an untreated population (108.4)

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10.1016/j.freeradbiomed.2014.06.023 Free Radic