Retatrutide produced 24.2% average weight loss at 48 weeks through triple receptor agonism (GIP/GLP-1/Glucagon), while Survodutide achieved 14.9-18.7% weight loss at 46 weeks through dual receptor agonism (GLP-1/Glucagon)
By mimicking the natural hormone GLP-1, these medications offer a multifaceted approach to managing blood sugar, reducing appetite, promoting weight loss, and even improving cardiovascular health
The most common side effects include abdominal pain, nausea, vomiting, constipation, diarrhea, indigestion, and headache
Natalie Hernandez partners with families to uncover the underlying causes of metabolic disease and create personalized treatment plans built around long-term health, not quick fixes
For RNAi experiments, cells were transfected with Control versus Target (VAPB or SPHKAP) siRNA